| Invention Title |
Inventor Name(s) |
|
3-Dimensional Structure of Tissue Transglutaminase for Small Molecule Design |
Richard Cerione,
Jon Clardy,
Shenping Liu
|
|
A Novel Approach for Discovery and Development of Alzheimer's Disease Therapeutics Based on Pin-1-catalyzed Conformation Changes in Phosphorylated Amyloid Precursor Protein |
Linda Nicholson,
Soumya De,
Kun Lu,
Lucia Pastorino,
Xiao Zhou
|
|
A Novel Class of Inhibitors of Beta-amyloid Peptide Aggregation, a Key Step in the Pathogenesis of Alzheimer's Disease |
George Hess,
Moataz Gadalla
|
|
Administration of Noggin and BDNF to Promote Neurogenesis |
Steven Goldman,
Eva Chmielnicki,
Aris Economides
|
|
Analogs of a B Vitamin (Nicotinamide Riboside, NR), and Efficient, Stereoselective Methods to Synthesize such Analogs
|
Anthony Sauve,
Tianle Yang
|
|
Anti-Amyloid Peptide Antibody Based Diagnosis and Treatment of a Neurological Disease or Disorder |
Marc Weksler,
Paul Szabo
|
|
Blood brain barrier model system: immortalized human brain endothelial cell line |
Babette Weksler,
Pierre Couraud,
Ignacio Romero
|
|
Chemical Inhibitors of Soluble Adenylyl Cyclase (sAC) |
Jochen Buck,
Lonny Levin,
Fritz Muhlschlegel
|
|
CLN2 Treatment for Alzheimers Disease |
Frederick Maxfield,
Lobel Peter
|
|
Compounds that Induce Arginase 1 to Enhance Neuroprotection |
Rajiv Ratan,
Juan Chavez,
Philipp Lange
|
|
Compounds that Promote Cholesterol Efflux from Cells |
Frederick Maxfield,
Amy Huang,
Nina Pipalia,
Harold Ralph,
Madalina Rujoi,
Anthony Sauve
|
|
Convenient Optical Design for Multiphoton Microscopy Incorporation into Medical Endoscopy Instrumentation |
Watt Webb,
Chunhui Xu
|
|
Device and Method to Quantify and Extract Sensorimotor Circuitry |
Francisco Valero-Cuevas,
Daniel Brown
|
|
Diagnosis of Normal Pressure Hydrocephalus by Automated Post Processing of MR Diffusion Images |
Aziz Ulug
|
|
Dopamine-producing stem cells for Parkinson's Disease |
Steven Goldman,
Takahiro Nakano,
Neeta Roy
|
|
Enrichment of Oligodendrocyte Precursor Cells from Postnatal and Adult Central Nervous System |
Steven Goldman,
Peter Braun,
Su Wang
|
|
Gene Therapy-Mediated Induction of Neuronal Production in the Adult Brain |
Steven Goldman,
Abdel-latif Benraiss
|
|
Human Neuronal Progenitor Cells |
Steven Goldman,
Maiken Nedergaared
|
|
Identification and Isolation of Multipotential Neural Progenitor Cells In Vitro from the Subcortical White Matter of the Adult Human Brain |
Steven Goldman,
Neeta Roy
|
|
Implanted Brain Monitoring Device |
Hongtao Ma,
Theodore Schwartz,
Jian-young Wu
|
|
Improved Golgi Stain for Visualizing Neural Cells |
Francis Lee,
Deqiang Jing
|
|
In-Vivo Alzheimer's Diagnostic Using Multiphoton Microscopy
(Joint Owner is Mass. Gen. Hospital Ref. No. 1705) |
Watt Webb,
Brian Bacskai,
Richard Christie,
Bradley Hyman,
Warren Zipfel
|
|
Induction and Isolation of Engraftable Human Spinal Motor Neurons from Human Embryonic Stem Cells |
Steven Goldman,
Takahiro Nakano,
Neeta Roy
|
|
Inhibitors of ATF4 - A Pro-death Transcription Factor in Neurons |
Rajiv Ratan,
Philipp Lange
|
|
Intermediate Duration Neuromuscular Blockers |
John Savarese,
Scott Van Ornum
|
|
Isolated Aminoarginine and Use to Block Nitric Oxide Formation |
Owen Griffith,
Steven Gross,
Roberto Levi
|
|
Isolation and Enrichment of Neural Stem Cells from Embryonic and Adult Central Nervous System |
Steven Goldman,
Hideyuki Okano
|
|
Metabotropic Glutamate Receptor 8 (mGluR8) knockout mice |
Robert Duvoisin
|
|
Metabotropic Glutamate Receptor Agonists in the Treatment of Cerebral Ischemia |
Kenneth Maiese
|
|
Method for Separating Cells |
Steven Goldman,
Hong Wu
|
|
Method to Isolate Embryonic Stem Cells Directed to Forebrain Interneuron Fate |
Stewart Anderson,
Asif Maroof,
Lorenz Studer
|
|
Methods for Designing Specific Ion Channel Blockers |
Xin-Yun Huang
|
|
Methods to drive differentiation of stem cells to neurons or glial cells |
Steven Goldman,
Fraser Sim
|
|
Methods to Objectively Stage and Diagnose Neurodegenerative CAG-Expansion Diseases |
John Blass,
Arthur Cooper
|
|
Molecular Analysis of Skin Biopsies in the Diagnosis of CIDP and Inflammatory Neuropathies |
Norman Latov,
Grace Lee
|
|
Monoclonal Antibodies to Tctex-1 (M17) |
Ching-Hwa Sung
|
|
Mouse Expressing Tagged BDNF Protein |
Barbara Hempstead
|
|
Mouse with BDNF Val(66)Met Polymorphism |
Francis Lee,
Zhe-Yu Chen,
Barbara Hempstead
|
|
Multiphoton Endoscopy through Fiber Optics |
Watt Webb
|
|
Multiplexed Biomarkers for Alzheimer's Disease Diagnosis |
Kelvin Lee,
Erin Finehout,
Norman Relkin
|
|
New Neuroprotectant Uses for FDA-Approved Compounds
|
Bruce Kristal,
M. Flint Beal,
Robert Friedlander
|
|
Non-Ocular Circadian Clock Resetting in Humans |
Scott Campbell,
Patricia Murphy
|
|
Novel Somatic Isoform of sAC, Present and Active in Putative sac KO Mouse |
Jochen Buck,
Jeanne Farrell,
Lonny Levin
|
|
Optical Fiber Delivery and Collection System for Biological Applications Such As Multiphoton Microscopy, Spectroscopy and Endoscopy |
Watt Webb,
Alexander Gaeta,
Dimitre Ouzounov,
Rebecca Williams,
Warren Zipfel
|
|
p21 Inducers as Neuroprotective and Anticancer Agents |
Brett Langley,
Melissa D'Annibale-Tolhurst,
Brian Ko,
Rajiv Ratan
|
|
Patient Controlled Brain Repair System |
Nicholas Schiff
|
|
Pineal Cell Lines (PGT-beta and PGT811) |
Jin Son
|
|
Polyclonal Antibodies to Tctex-1 |
Ching-Hwa Sung,
Jen-Zen Chuang
|
|
Promoter of the Rat Tyrosine Hydroxylase Gene for Tissue Specific Gene Expression |
Jin Son,
Tong Joh,
Nan Min
|
|
Promoter Region as Stem Cell Marker |
Ching-Hwa Sung,
Jen-Zen Chuang
|
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